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Levitra Super Active Overview

Characteristic Details
Active Ingredient Vardenafil
Available Dosages 20 mg
Form Soft Gel Capsule
Usage Oral Administration
Prescription Requirement Yes
Learn More About Levitra Super Active

Pharmacokinetics

Levitra Super Active 20 mg undergoes rapid absorption post-ingestion. Maximum plasma concentration is achieved within 30 to 120 minutes. The absorption rate varies depending on concurrent food intake, though the effect remains largely consistent. Distribution through the body is extensive, with a large volume of distribution indicating its high tissue affinity.

Metabolism occurs primarily in the liver via the cytochrome P450 enzyme system. This process involves multiple isoenzymes, predominantly CYP3A4, CYP3A5, and CYP2C. Excretion is mainly through fecal elimination, with a minor portion excreted in urine. The elimination half-life of vardenafil is approximately 4 to 5 hours, suggesting a relatively moderate duration of activity.

Mechanism of Action

The therapeutic effect of vardenafil stems from its role as a selective phosphodiesterase type 5 (PDE5) inhibitor. By inhibiting this enzyme, it enhances the level of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. Elevated cGMP levels promote smooth muscle relaxation and increased blood flow, facilitating erection during sexual arousal.

This mechanism of action is specific to the genitalia, minimizing systemic effects. Vardenafil’s selectivity for PDE5 over other phosphodiesterases reduces the risk of off-target activity, a crucial feature for patient safety.

FDA-Approved Indications

Levitra Super Active 20 mg has received FDA approval for treating erectile dysfunction (ED). It is indicated for use in adult men experiencing difficulty achieving or maintaining an erection sufficient for satisfactory sexual performance. The approval is based on extensive clinical trials demonstrating efficacy and safety.

ED is a prevalent condition affecting many men, and this treatment offers a reliable therapeutic option. Levitra Super Active addresses a significant need within this patient population, providing a medically endorsed solution.

Cautions with Other Medicines

Drug interactions represent a critical consideration with Levitra Super Active. Concomitant use with nitrates, often prescribed for angina, can cause severe hypotension. Alpha-blockers and other antihypertensives may also interact, necessitating careful management to avoid adverse cardiovascular events.

Other potential interactions include drugs affecting the CYP3A4 enzyme system. This includes certain antibiotics, antifungals, and antiviral medications. Patients should disclose their full medication regimen to their healthcare provider before initiating treatment.

Effects of Levitra Super Active

The primary effect of Levitra Super Active is the enhancement of erectile function. It improves the ability to achieve and maintain an erection suitable for sexual activity. Its quick onset and reliable duration of action make it a preferred choice for many men with ED.

Common side effects include headache, flushing, and nasal congestion. These effects are generally mild and transient. More serious adverse reactions are rare but warrant immediate medical attention.

Is Non-Prescription Levitra Super Active Available?

Levitra Super Active is not available as a non-prescription medication. It requires a healthcare provider’s evaluation and prescription. This ensures appropriate use and monitoring for potential interactions or side effects.

The prescription status underscores its role as a targeted therapy for erectile dysfunction. Patients should consult with their healthcare providers to determine if this treatment aligns with their medical needs.

  • Improves erectile function
  • Rapid onset of action
  • Requires prescription

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